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Tangram 是一个基于scanpy的 Python 包,用PyTorch编写,用于将单细胞(或单核)基因表达数据映射到空间基因表达数据上。单细胞数据集和空间数据集应来自同一解剖区域/组织类型,理想情况下来自同一生物学重复,并且需要共享一组基因。Tangram 通过拟合共享基因的基因表达来在空间上对齐单细胞数据。
Scanpy 是一个可扩展的工具包,用于分析与anndata联合构建的单细胞基因表达数据。它包含预处理、可视化、聚类、轨迹推断和差异表达测试等功能。该工具包基于 Python 实现,可高效处理超过一百万个细胞的数据集。
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